Which two vitamins are needed in large amounts during pregnancy due to rapid cell proliferation?

During pregnancy, the need for certain vitamins increases significantly to support the rapid growth and development of the fetus as well as the overall health of the mother. Folate, also known as vitamin B9, is critical during pregnancy as it plays a crucial role in DNA synthesis and cell division. It helps prevent neural tube defects in the developing fetus, making it one of the most important nutrients during this period.

Vitamin B12 is also essential as it works closely with folate in the production of red blood cells and ensures proper neurological function. Both vitamins are required in larger amounts due to the increased metabolic demands and the proliferation of cells occurring during this time.

The combination of folate and B12 is particularly significant because they both work in synergy to maintain adequate levels of homocysteine, which is important for cardiovascular health and neurological development in the fetus. This need is compounded by the fact that deficiencies in either can lead to severe complications, such as anemia and developmental issues.

While other B vitamins mentioned may contribute to overall health, they do not have the same level of critical importance and requirement during pregnancy as folate and B12.